Research shows exercise improves quality of life for people with metastatic breast cancer

New research shows that a regular, supervised exercise program can make a significant difference for people living with metastatic breast cancer.

Not only does it improve their quality of life, it also helps reduce healthcare costs.

The PREFERABLE-EFFECT trial – a world-first study involving 357 people worldwide including 135 Australians – found that just two hours of supervised weekly exercise can have life-changing effects.

The nine-month program included a mix of aerobic, resistance, and balance exercises.

Participants saw improvements in their energy levels, reduced pain, and felt less emotional distress. 

These benefits helped them lead more active and fulfilling lives.

"These unique findings from our multinational PREFERABLE-EFFECT study are particularly important for healthcare providers, policymakers, and insurers,” said Dr Eva Zopf, a Melbourne-based exercise physiologist and lead researcher.

“They demonstrate that supervised exercise for patients with metastatic breast cancer is not only beneficial in improving quality of life and reducing treatment-related side effects but also reduces healthcare costs."

Why these findings matter

Metastatic breast cancer is treatable but not curable. As more people are living longer with metastatic breast cancer, it’s vital we know how to support them.

Exercise programs can improve quality of life

This study shows that supervised exercise programs are a powerful tool to help manage the challenges living with metastatic breast cancer brings.

Participants in the program experienced significant improvements in quality of life, with reductions in debilitating symptoms such as fatigue, pain, and emotional distress, enabling them to lead fuller, more active lives.

Exercise programs bring economic benefits

The study also found that supervised exercise programs save money by reducing the need for hospital visits, home care, and other healthcare services.

Notably, 44% of participants in the study were in paid employment, and the exercise group demonstrated lower productivity losses compared to the control group.

Those in group-based exercise classes saw the greatest benefit, saving nearly $2,000 per person compared to those who received individual supervision or general activity advice.

Programs like these also help reduce the rising costs of cancer care in Australia, which exceed $1 billion every year.

Dr Eva Zopf added: "This study proves that supervised exercise is not just about feeling better. It also helps reduce healthcare costs, which makes it a win-win for patients and the healthcare system."

Better support is still needed

BCNA welcomed these findings and is calling for exercise programs to be a standard part of care for people with metastatic breast cancer.

"For people living with metastatic breast cancer, managing symptoms like fatigue, pain, and emotional distress is crucial," said Vicki Durston, BCNA’s Director of Policy, Advocacy & Support Services.  

"This study shows how important supportive care, like exercise, is for helping people live their best lives. It’s time to make programs like these a regular part of cancer care - not just a recommendation."

The study underscores the urgent need for national data collection and tailored care. Recent data from New South Wales revealed a higher number of people living with metastatic breast cancer than previously estimated, yet they remain underserved in research and healthcare planning.

BCNA will continue to push for stronger support systems and evidence-based care to ensure everyone affected by breast cancer gets the help they need.

Background

Media release, 17 Jan 2025: Supervised exercise program for people with incurable breast cancer reveals significant health and economic benefits: world-first data